H. pylori - Ace Therapeutics
H. pylori Infection
Online Inquiry

H. pylori Infection

Introduction of H. pylori Infection

Helicobacter pylori (H. pylori) is a common bacterial infection that affects the stomach lining, leading to various gastrointestinal issues. This article aims to provide a comprehensive overview of H. pylori infection, including its causes, symptoms, diagnosis, and treatment options.

H. pylori Infection

Causes of H. pylori Infection

H. pylori infection occurs when the bacterium H. pylori enters the body, usually through contaminated food or water. The exact transmission routes are not yet fully understood, but it is believed that person-to-person contact, poor hygiene, and unsanitary living conditions play a role. Additionally, factors such as a weakened immune system and certain genetic predispositions may increase the risk of infection. It is important to note that the infection is not caused by consuming spicy or acidic foods, as was previously believed.

Symptoms of H. pylori Infection

Many individuals infected with H. pylori do not experience any noticeable symptoms. However, when symptoms do occur, they can vary in severity. Common symptoms include persistent abdominal pain, bloating, nausea, vomiting, loss of appetite, unexplained weight loss, and black or tarry stools indicating gastrointestinal bleeding. In some cases, the infection can lead to peptic ulcers or stomach inflammation (gastritis). Additionally, H. pylori infection has been associated with an increased risk of developing stomach cancer, although the majority of infected individuals do not develop this complication.

Diagnosing H. pylori Infection

To diagnose H. pylori infection, healthcare professionals may perform various tests. These can include a blood test to detect antibodies against the bacterium, a breath test to measure the presence of H. pylori-related compounds, a stool antigen test, or an endoscopy with tissue biopsy. Endoscopy involves inserting a flexible tube with a camera into the esophagus and stomach to visualize the digestive tract and obtain tissue samples for analysis. The choice of diagnostic method depends on several factors, such as the individual's symptoms, medical history, and the availability of testing facilities.

Treatment Options for H. pylori Infection

The treatment of H. pylori infection typically involves a combination of antibiotics and acid-reducing medications. Antibiotics, such as amoxicillin and tetracycline, are used to eradicate the bacteria. Acid-reducing medications, including proton pump inhibitors (PPIs) or histamine H2-receptor blockers, help reduce stomach acid production and promote healing of the stomach lining. The specific antibiotic regimen and duration of treatment vary depending on factors such as the individual's age, medical history, and antibiotic resistance patterns in the local population. It is crucial to complete the full course of treatment as prescribed by the healthcare professional to ensure successful eradication of the infection.


Helicobacter pylori infection is a prevalent gastrointestinal condition that can lead to various symptoms and complications. Early detection and appropriate treatment are crucial to prevent further health issues. If you suspect you may have an H. pylori infection, it is important to consult a healthcare professional for accurate diagnosis and personalized treatment.


  1. Fischbach W, Malfertheiner P. Helicobacter Pylori Infection. Dtsch Arztebl Int. 2018, 115(25):429-436.

※ All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.